Research Database

Measuring free-living physical activity in COPD patients: Deriving methodology standards for clinical trials through a review of research studies

  • Added on July 12, 2016

Abstract: This article presents a review of the research literature to identify the methodology used and outcome measures derived in the use of accelerometers to measure free-living activity in patients with COPD. Using this and existing empirical validity evidence we further identify standards for use, and recommended clinical outcome measures ...


Physical Activity as a Predictor of Thirty-Day Hospital Re-Admission after a Discharge for a Clinical Exacerbation of COPD

  • Published on Aug. 28, 2014

Rationale: Physical inactivity in COPD predicts health care utilization and mortality. Objectives: To prospectively evaluate the relationship of this variable to the frequency of 30-day readmissions. Methods: Following a hospitalization for an exacerbation, consented patients discharged following an exacerbation of COPD were asked to wear an ActiGraph GT3X+ accelerometer ...


Directly-Measured Physical Activity Predicts Re-Hospitalization Within Thirty Days Following Discharge For A COPD Exacerbation

  • Presented on May 19, 2014

Background: Lower levels of physical activity are related to increased health care utilization and mortality risk in patients with COPD. Since re-hospitalization within 30 days following discharge for a COPD exacerbation is considered an important outcome, we evaluated the relationship between physical activity and 30-day readmission. Methods: Thirty-four patients discharged following ...


Association Between Physical Activity and Inflammatory Markers Among U.S. Adults with Chronic Obstructive Pulmonary Disease

  • Published on Dec. 20, 2013

Purpose: Chronic obstructive pulmonary disease (COPD) may cause not only inflammation in the lungs but also systemic effects. One potential strategy to reduce systemic inflammation and attenuate disease progression is physical activity (PA). However, no nationally representative studies, to our knowledge, have examined the association between objectively measured physical activity ...


Validity of physical activity monitors during daily life in patients with COPD

  • Published on Nov. 1, 2013

Background: Symptoms during physical activity and physical inactivity are hallmarks of chronic obstructive pulmonary disease (COPD). Our aim was to evaluate the validity and usability of six activity monitors in patients with COPD against the doubly labelled water (DLW) indirect calorimetry method. Methods: 80 COPD patients (mean±SD age 68±6 years and ...


Reliability and validity of the multimedia activity recall in children and adults (MARCA) in people with chronic obstructive pulmonary disease.

  • Published on Nov. 27, 2013

Objective: To determine the reliability and validity of the Multimedia Activity Recall for Children and Adults (MARCA) in people with chronic obstructive pulmonary disease (COPD). Design: People with COPD and their carers completed the Multimedia Activity Recall for Children and Adults (MARCA) for four, 24-hour periods (including test-retest of 2 days) ...


Study to Evaluate the Impact of the “PROactive Telecoaching Program” on Physical Activity in Patients With COPD.

  • Added on March 10, 2014

Sponsor: Novartis Pharmaceuticals Collaborators: Innovative Medicines Initiative (PROactive Project), Innovative Medicines Initiative. Information provided by (Responsible Party): Novartis (Novartis Pharmaceuticals) Clinicaltrials.gov Identifier: NCT01992081 Purpose: This study will test two instruments to measure physical activity in COPD patients: A questionnaire and two small physical activity monitors .Patients will be randomized ...


A Longitudinal Study Evaluating the Effect of Exacerbations on Physical Activity in Patients with COPD

  • Published on Sept. 20, 2013

Background Physical inactivity is common in stable COPD and independently predicts poor outcomes. Longitudinal assessments of physical activity in outpatients with COPD, covering periods of stability and exacerbations, have not been evaluated previously. Methods Patients with clinically-stable COPD and a history of 2 or more clinical exacerbations in the preceding 12 months ...


Annual recollection of exacerbations in patients with COPD: Impact on physical activity

  • Presented on Sept. 9, 2013

Rationale The number of exacerbations in the previous year has shown to be the best predictor of new exacerbations. The ability to recall exacerbations may lead to misclassification of patients and may have consequences on patients’ phenotype. Methods 47 patients with COPD (FEV1 65±21%pred) reported on a monthly basis all health ...


Agreement of classification of COPD patients’ physical activity with two activity monitors

  • Presented on Sept. 8, 2013

Rationale It is unclear whether different activity monitors provide similar classification of physical activity (PA) in patients with COPD. Aim To test whether similar PA classification of patients would be obtained when using 2 valid activity monitors. Methods We assessed PA for 4 weeks with Actigraph [(ACT: Steps and vector magnitude units (...